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Texas Red TCO *Single isomer*
The tetrazine-trans-cyclooctene (TCO) ligation constitutes a non-toxic biomolecule labeling method of unparalleled speed. A tetrazine-functionalized molecule reacts with a TCO-functionalized molecule, forming a stable conjugate via a dihydropyrazine moiety. This inverse electron demand cycloaddition reaction has gained popularity due to the potential for extremely fast cycloaddition kinetics with TCO as the dienophile. AAT Bioquest offers a group of tetrazine- and TCO-containing dyes for exploring various biological systems that can use this powerful click reaction. Texas Red-TCO can be readily used to label tetrazine-modified biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. It is widely used for labeling tetrazine-modified peptides, proteins and oligos etc.
Spectrum
Product family
| Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield | Correction Factor (260 nm) | Correction Factor (280 nm) | Correction Factor (565 nm) |
| Texas Red® alkyne *Single Isomer* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
| Texas Red® azide *Single Isomer* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
| Texas Red® cadaverine *Single Isomer* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
| Texas Red-DHPE *CAS 187099-99-6* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
| Texas Red® hydrazide *Single Isomer* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
| Texas Red® maleimide *Single Isomer* | 586 | 603 | 1160001 | 0.971, 0.932 | 0.23 | 0.36 | 0.4472 |
References
View all 50 references: Citation Explorer
Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands.
Authors: van de Graaff, Michel J and Oosenbrug, Timo and Marqvorsen, Mikkel H S and Nascimento, Clarissa R and de Geus, Mark A R and Manoury, Bénédicte and Ressing, Maaike E and van Kasteren, Sander I
Journal: Bioconjugate chemistry (2020): 1685-1692
Authors: van de Graaff, Michel J and Oosenbrug, Timo and Marqvorsen, Mikkel H S and Nascimento, Clarissa R and de Geus, Mark A R and Manoury, Bénédicte and Ressing, Maaike E and van Kasteren, Sander I
Journal: Bioconjugate chemistry (2020): 1685-1692
Titanium coating with mussel inspired polymer and bio-orthogonal chemistry enhances antimicrobial activity against Staphylococcus aureus.
Authors: Czuban, Magdalena and Kulka, Michaël W and Wang, Lei and Koliszak, Anna and Achazi, Katharina and Schlaich, Christoph and Donskyi, Ievgen S and Di Luca, Mariagrazia and Mejia Oneto, Jose M and Royzen, Maksim and Haag, Rainer and Trampuz, Andrej
Journal: Materials science & engineering. C, Materials for biological applications (2020): 111109
Authors: Czuban, Magdalena and Kulka, Michaël W and Wang, Lei and Koliszak, Anna and Achazi, Katharina and Schlaich, Christoph and Donskyi, Ievgen S and Di Luca, Mariagrazia and Mejia Oneto, Jose M and Royzen, Maksim and Haag, Rainer and Trampuz, Andrej
Journal: Materials science & engineering. C, Materials for biological applications (2020): 111109
Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies.
Authors: Nazarova, Lidia and Rafidi, Hanine and Mandikian, Danielle and Ferl, Gregory Z and Koerber, James T and Davies, Christopher W and Ulufatu, Sheila and Ho, Jason and Lau, Jeffrey and Yu, Shang-Fan and Ernst, James and Sadowsky, Jack D and Boswell, C Andrew
Journal: Molecular cancer therapeutics (2020): 1052-1058
Authors: Nazarova, Lidia and Rafidi, Hanine and Mandikian, Danielle and Ferl, Gregory Z and Koerber, James T and Davies, Christopher W and Ulufatu, Sheila and Ho, Jason and Lau, Jeffrey and Yu, Shang-Fan and Ernst, James and Sadowsky, Jack D and Boswell, C Andrew
Journal: Molecular cancer therapeutics (2020): 1052-1058
Tetrazine Carbon Nanotubes for Pretargeted In Vivo "Click-to-Release" Bioorthogonal Tumour Imaging.
Authors: Li, He and Conde, João and Guerreiro, Ana and Bernardes, Gonçalo J L
Journal: Angewandte Chemie (International ed. in English) (2020)
Authors: Li, He and Conde, João and Guerreiro, Ana and Bernardes, Gonçalo J L
Journal: Angewandte Chemie (International ed. in English) (2020)
A Pretargeted Imaging Strategy for Immune Checkpoint Ligand PD-L1 Expression in Tumor Based on Bioorthogonal Diels-Alder Click Chemistry.
Authors: Qiu, Lin and Tan, Hui and Lin, Qingyu and Si, Zhan and Mao, Wujian and Wang, Tingting and Fu, Zhequan and Cheng, Dengfeng and Shi, Hongcheng
Journal: Molecular imaging and biology (2020): 842-853
Authors: Qiu, Lin and Tan, Hui and Lin, Qingyu and Si, Zhan and Mao, Wujian and Wang, Tingting and Fu, Zhequan and Cheng, Dengfeng and Shi, Hongcheng
Journal: Molecular imaging and biology (2020): 842-853
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