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XFD350 Anti-human CD11a Antibody
HI111
HI111 is an anti-human monoclonal antibody that forms an immune complex with the CD11a antigen. CD11a (also known as Integrin alpha-L or LFA-1α chain) is a 170 - 180 kD transmembrane protein that is expressed on the surface of cells such as granulocytes and macrophages. CD11a has been associated with critical biological processes like cell-cell adhesion, especially leukocyte cell-cell adhesion. Moreover, it is a member of essential cellular pathways, for instance, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as CD18 and ICAM-1, 2, 3 and 4. CD11a is a fairly uncommon antibody target, with a little more than 3700 publications in the last decade. Even still, CD11a has a variety of applications in neuroscience and innate immunity research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD350 (ex/em = 343/441 nm). XFD350 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 350 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 355 nm laser and 450/50 nm bandpass filter (for example, as in the BD LSRFortessa™ Cell Analyzer).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10110140 | 100 tests | Price | |
| 10110141 | 500 tests | Price |
Antibody properties
| Other names | LFA-1A, Integrin aL, ITGAL |
| Clone | HI111 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.25 |
| Correction factor (280 nm) | 0.19 |
| Extinction coefficient (cm -1 M -1) | 19000 |
| Excitation (nm) | 343 |
| Emission (nm) | 441 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 1, 2026