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XFD350 Anti-human CD11c Antibody
3.9
3.9 is an anti-human monoclonal antibody that forms an immune complex with the CD11c antigen. CD11c (sometimes called CR4 or ITGAX) is a 145 - 150 kD single-pass type I membrane protein that is expressed on the surface of cells such as macrophages, B cells and dendritic cells. In some organisms, CD11c promotes angiogenesis, positively regulates myelination and is a promoter of endothelial tube morphogenesis. Moreover, it is a component of essential cellular pathways, in particular, the cytokine-mediated signaling pathway and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and 4 and fibrinogen. CD11c is a very popular antibody target, with over 26000 publications in the last decade. CD11c has been widely used in costimulatory molecules research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD350 (ex/em = 343/441 nm). XFD350 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 350 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 355 nm laser and 447/60 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10113140 | 100 tests | Price | |
| 10113141 | 500 tests | Price |
Antibody properties
| Other names | Integrin alpha-X, CR4, p150, ITGAX |
| Clone | 3.9 |
| Host | Mouse |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.25 |
| Correction factor (280 nm) | 0.19 |
| Extinction coefficient (cm -1 M -1) | 19000 |
| Excitation (nm) | 343 |
| Emission (nm) | 441 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on June 19, 2026