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XFD488 Anti-human CD107 Antibody
H4B4
H4B4 is an anti-human monoclonal antibody that targets the CD107b antigen. CD107b (sometimes called LAMP2 or LAMPb) is a 45 kD transmembrane protein that is found on the surface of cells like granulocytes and endothelial cells. In many organisms, CD107 is a suppressor of protein-containing complex assembly. Additionally, it has been associated with essential biological processes like chaperone-mediated autophagy, particularly protein targeting to lysosome involved in chaperone-mediated autophagy. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD107 is a relatively rare antibody target, with fewer than 800 publications in the last decade. Even still, CD107b is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of protein trafficking and clearance and neuroscience. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 488 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 488 nm laser and 530/30 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 11071140 | 100 tests | Price | |
| 11071141 | 500 tests | Price |
Antibody properties
| Other names | LAMP2, LAMPb |
| Clone | H4B4 |
| Host | Mouse |
| Isotype | Mouse IgG1 kappa |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.30 |
| Correction factor (280 nm) | 0.11 |
| Extinction coefficient (cm -1 M -1) | 71000 |
| Excitation (nm) | 499 |
| Emission (nm) | 520 |
| Quantum yield | 0.92 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on December 18, 2025