Name: XFD488 Anti-human CD123 Antibody *12H7*
Brand: AAT Bioquest
SKU: 11231140
Availability: InStock

XFD488 Anti-human CD123 Antibody

12H7

The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells. CD123 acts in vital cellular pathways, for instance, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like CD131. CD123 is a fairly uncommon antibody target, with a little more than 3900 publications in the last decade. Even still, CD123 is essential for immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 488 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 488 nm laser and 525/40 nm bandpass filter (for example, as in the Beckman Coulter DxFLEX).

Datasheet

COA

Catalog	Size	Price	Quantity
11231140	100 tests	Price
11231141	500 tests	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of CD123 antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Other names	IL-3Rα
Clone	12H7
Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Application	Flow Cytometry (FACS), Fluorescence Imaging

Spectral properties

Correction factor (260 nm)	0.30
Correction factor (280 nm)	0.11
Extinction coefficient (cm ^-1 M ^-1)	71000
Excitation (nm)	499
Emission (nm)	520
Quantum yield	0.92 ¹

Usage and storage

Intended use

Research Use Only (RUO)

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Page updated on August 19, 2026