Products
Services
Resources
Selection Guides
About
XFD488 Anti-non-human primates/ human CD35 Antibody
E11
E11 is an anti-non-human primates/ human monoclonal antibody that recognizes the CD35 antigen. CD35 (alternatively called Complement receptor type 1) is a single-pass type I membrane protein that is found on the surface of cells such as erythrocytes. CD35 plays a role in key cellular pathways, for example, the negative regulation of complement activation, alternative pathway and complement activation, classical pathway. Moreover, in certain organisms, it represses serine-type endopeptidase activity, plays a role in the downregulation of complement activation, alternative pathway and is involved in the positive regulation of serine-type endopeptidase activity. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as ic3, c4b, c3b and ic4. CD35 is a fairly uncommon antibody target, with a little more than 1800 publications in the last decade. Even still, CD35 has been widely used in immunology, cell biology and neuroinflammation research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 488 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 488 nm laser and 525/50 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant Analyzer 16).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10350150 | 100 tests | Price | |
| 10350151 | 500 tests | Price |
Antibody properties
| Other names | C3b/C4b receptor, Complement receptor type 1 |
| Clone | E11 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Non-Human Primates, Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.30 |
| Correction factor (280 nm) | 0.11 |
| Extinction coefficient (cm -1 M -1) | 71000 |
| Excitation (nm) | 499 |
| Emission (nm) | 520 |
| Quantum yield | 0.92 1 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 22, 2026