XFD488 Anti-rabbit/ ferret/ cow/ human CD88 Antibody *S5/1*

S5/1 is an anti-rabbit/ ferret/ cow/ human monoclonal antibody that forms an immune complex with the CD88 antigen. CD88 (also known as C5R1 or C5AR) is a 43 kD transmembrane glycoprotein that is expressed on the surface of cells like endothelial cells, dendritic cells, granulocytes and macrophages. CD88 is associated with a variety of biologically interesting macromolecules/ligands, for example, anaphylatoxin. CD88 is a relatively rare antibody target, with fewer than 700 publications in the last decade. Even still, CD88 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and cell biology. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 488 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 488 nm laser and 530/30 nm bandpass filter (for example, as in the BD LSRFortessa™ Cell Analyzer).

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