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XFD555 Anti-non-human primates/ human CD177 Antibody
MEM-166
MEM-166 is an anti-non-human primates/ human monoclonal antibody that targets the CD177 antigen. CD177 (sometimes referred to as Neutrophil-specifi c antigen 1, PRV1 or NB1gp) is a 60 kD member of the uPAR family that is expressed on the surface of cells like granulocytes. CD177 plays a role in critical cellular pathways, namely, the regulation of integrin-mediated signaling pathway. In addition, it has been associated with vital biological processes such as leukocyte cell-cell adhesion, particularly cell-cell adhesion via plasma-membrane adhesion molecules. In some organisms, CD177 is an enhancer of superoxide anion generation, and is associated with a variety of biologically interesting macromolecules/ligands. CD177 is a relatively rare antibody target, with fewer than 600 publications in the last decade. Even still, CD177 is essential for immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD555 (ex/em = 553/568 nm). XFD555 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 555 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ III).
product image
CatalogSize
Price
Quantity
11770150100 tests
Price
11770151500 tests
Price
 
Antibody properties

Other namesNB1gp, HNA-2a, NB1, Neutrophil-specifi c antigen 1, PRV1
CloneMEM-166
HostMouse
IsotypeIgG1
ReactivityNon-Human Primates, Human
ApplicationFlow Cytometry (FACS), Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.08
Correction factor (280 nm)0.08
Extinction coefficient (cm -1 M -1)
150000
Excitation (nm)553
Emission (nm)568
Quantum yield
0.1
1
Usage and storage

Intended useResearch Use Only (RUO)
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Page updated on August 20, 2026