XFD594 Anti-human/monkey CD154 Antibody *5C8*

5C8 is an anti-human/monkey monoclonal antibody that forms an immune complex with the CD154 antigen. CD154 (also known as gp39) is a 32 - 39 kD member of the TNF superfamily that is expressed on the surface of cells such as T cells. CD154 is associated with a variety of biologically interesting macromolecules/ligands, for instance, CD40. CD154 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD154 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to XFD594 (ex/em = 590/618 nm). XFD594 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 594 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 592 nm laser and 610/30 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).

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