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XFD647 Anti-human CD33 Antibody
HIM3-4
HIM3-4 is an anti-human monoclonal antibody that forms an immune complex with the CD33 antigen. CD33 (sometimes referred to as p67) is a 67 kD transmembrane glycoprotein that is located on the surface of cells such as macrophages and granulocytes. CD33 has been thought to be involved with important biological processes like signal transduction, specifically immune response-inhibiting signal transduction. Also, in certain organisms, it is a promoter of protein secretion, is an enhancer of protein tyrosine phosphatase activity and is a repressor of interleukin-8 production. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like α-2, Sugar chains containing sialic acid and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is essential for immunology, neuroinflammation and cell biology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD647 (ex/em = 650/671 nm). XFD647 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 647 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10331180 | 100 tests | Price | |
| 10331181 | 500 tests | Price |
Antibody properties
| Other names | Siglec-3, gp67 |
| Clone | HIM3-4 |
| Host | Mouse |
| Isotype | IgG1 |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.00 |
| Correction factor (280 nm) | 0.03 |
| Extinction coefficient (cm -1 M -1) | 239000 |
| Excitation (nm) | 650 |
| Emission (nm) | 671 |
| Quantum yield | 0.33 1 |
Usage and storage
| Intended use | Research Use Only (RUO) |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on August 7, 2026