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XFD647 Anti-human CD34 Antibody
4H11
4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen. CD34 (sometimes called Gp105-120) is a 105 - 120 kD glycoprotein that is located on the surface of cells like endothelial cells and stem cells. In many organisms, CD34 plays a role in the downregulation of tumor necrosis factor production, positively regulates granulocyte colony-stimulating factor production and is involved in the positive regulation of vasculogenesis. Also, it has been associated with vital biological processes such as endothelium development, especially glomerular endothelium development. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like MadCAM-1, CRKL and L-Selectin. CD34 is a very popular antibody target, with over 55000 publications in the last decade. CD34 is vital to neuroscience, neuroinflammation and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD647 (ex/em = 650/671 nm). XFD647 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 647 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 642 nm laser and 702/87 nm bandpass filter (for example, as in the Luminex Amnis CellStream).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10340180 | 100 tests | Price | |
| 10340181 | 500 tests | Price |
Antibody properties
| Other names | Gp105-120 |
| Clone | 4H11 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Human |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.00 |
| Correction factor (280 nm) | 0.03 |
| Extinction coefficient (cm -1 M -1) | 239000 |
| Excitation (nm) | 650 |
| Emission (nm) | 671 |
| Quantum yield | 0.33 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on March 2, 2026