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XFD680 Anti-mouse/human/rat CD47 Antibody
MIAP410
The MIAP410 monoclonal antibody binds with mouse/human/rat CD47, a 42 - 52 kD transmembrane protein frequently located on the surface of b cells, thymocytes and epithelial cells. In many organisms, CD47 acts to positively regulate phagocytosis, is a promoter of cell population proliferation and enhances T cell activation. Also, it is involved with vital cellular pathways, for instance, the negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis and integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like Thrombospondin, SIRP and CD61. CD47 is a fairly uncommon antibody target, with a little more than 5000 publications in the last decade. Even still, CD47 has a variety of applications in immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD680 (ex/em = 681/704 nm). XFD680 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 680 (Alexa Fluor® is the trademark of Thermo Fisher). It is compatible with the 642 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).
| Catalog | Size | Price | Quantity |
|---|---|---|---|
| 10473190 | 100 tests | Price | |
| 10473191 | 500 tests | Price |
Antibody properties
| Other names | gp42, IAP, neurophilin, MER6, Integrin associated protein |
| Clone | MIAP410 |
| Host | Mouse |
| Isotype | Mouse igg1, κ |
| Reactivity | Mouse, human, rat |
| Application | Flow Cytometry (FACS), Fluorescence Imaging |
Spectral properties
| Correction factor (260 nm) | 0.00 |
| Correction factor (280 nm) | 0.05 |
| Extinction coefficient (cm -1 M -1) | 184000 |
| Excitation (nm) | 681 |
| Emission (nm) | 704 |
| Quantum yield | 0.36 1 |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
Contact us
| Telephone | |
| Fax | |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Technical Support | Contact us |
| Request quotation | Request |
| Purchase order | Send to sales@aatbio.com |
| Shipping | Standard overnight for United States, inquire for international |
Page updated on December 21, 2025