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Can next-generation sequencing (NGS) be used for virus genomes?
Posted May 9, 2020
DNA and RNA QuantitationDNA and RNANucleic AcidsPCR Detection of Viral DNA/RNAPolymerase Chain Reaction (PCR)RNA
Answer
Although more difficult to sequence due to the low abundance of viral RNA compared to that of a host, it is entirely possible to use next-generation sequencing for viral genomes.
Additional resources
Marston, D. A., McElhinney, L. M., Ellis, R. J., Horton, D. L., Wise, E. L., Leech, S. L., ... & Fooks, A. R. (2013). Next generation sequencing of viral RNA genomes. BMC genomics, 14(1), 444.

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