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How can one distinguish naive from effector/effector memory CD8 T cells?

Posted May 9, 2020


Antibodies and Proteomics
Bioconjugation
Antibody and Protein Labeling
Cluster of Differentiation (CD Antibodies)
IHC
Immunohistochemistry (IHC)
Answer

Naive CD8 T cells are CD44 low and CD62L positive, while effector/effector memory CD8 T cells are CD44 high and CD62L negative.

Additional resources

Sckisel, G. D., Mirsoian, A., Minnar, C. M., Crittenden, M., Curti, B., Chen, J. Q., ... & Murphy, W. J. (2017). Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy. Journal for immunotherapy of cancer, 5(1), 33.

Cluster of Differentiation (CD Antibodies)

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Location: Home / Frequently Asked Questions (FAQ) / How can one distinguish naive from effector/effector memory CD8 T cells?
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