Fragment analysis is a genetic analysis technique that offers several advantages including:
High sensitivity – Allows researchers to accurately size fragments differing by only one base pair
Automated workflows – Allows researchers to run thousands of DNA fragment samples in one day
Easy data analysis – The genetic analysis software simplified data analysis
Simple preparation and cleanup – There’s no need to perform a DNA cleanup as opposed to other similar techniques such as sequencing
Multiplexing capability – Labeling locus-specific primers with different colored dyes makes it easier to distinguish alleles for overlapping loci, enabling the analysis of more than twenty loci in a single reaction
Ability to achieve high throughput – This can be done using capillary arrays
Ability to obtain relative quantitation information from peak intensity measurements
Independent method – Knowledge of the sequence of the fragment is not required