What are the applications of immobilized metal affinity chromatography (IMAC)? | AAT Bioquest

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What are the applications of immobilized metal affinity chromatography (IMAC)?

Posted December 14, 2021

Bioconjugation Antibody and Protein Labeling Antibodies and Proteomics

Answer

Immobilized metal affinity chromatography (IMAC) is used to purify proteins based on their affinity to specific metal ions. It is widely used to purify monoclonal antibodies, enzymes, blood factors, albumin, interferons, immunoglobulins, and many other proteins and polypeptides.

Additional resources

Immobilized-metal affinity chromatography (IMAC): a review IDA succinimidyl ester

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