AAT Bioquest

What are the common applications of PCR?

Posted February 9, 2022


PCR (polymerase chain reaction) facilitates the in vitro amplification of DNA fragments. This has a wide range of applications in diagnostics, genotyping, forensics, mutation detection, paternity testing, cloning, and microarrays.

Common applications of PCR include:

  • Study of gene expression
  • Analysis of genetic markers for forensic applications, mapping of hereditary traits, and paternity testing
  • Modification of DNA fragments
  • DNA analysis of archaeological specimens
  • Amplification of gene fragments as an alternative of cloning
  • Detection of mutations relevant for tissue typing, inherited diseases or malignant transformation
  • Detection of pathogenic microorganisms
Additional resources

The applications of the polymerase chain reaction in the life sciences

Polymerase Chain Reaction (PCR)