What are the differences between ion exchange chromatography and affinity chromatography?

Ion exchange chromatography:

• Is a form of liquid chromatography that’s used to separate charged particles
• Is based on the interaction between the column and the target molecule that has an opposite charge to that of the stationary phase surface
• Examples: inorganic cations and anions, organic ions, and proteins

 Affinity chromatography:

• Is used to separate components in a mixture
• Is based on the interactions between the target and the stationary phase surface
• Can be used to separate charged or uncharged components in a mixture
• Examples: enzymes, substrates, DNA, antigens, proteins, and antibodies