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AAT Bioquest

What is Immobilized Metal Chelate Affinity Chromatography (IMAC)?

Posted December 14, 2021


Answer

Immobilized metal affinity chromatography (IMAC) is a highly efficient technique used to separate proteins based on the interaction between proteins in solution and transition metal ions fixed to a solid support.

Additional resources

Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors

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