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AAT Bioquest

What is an organotypic culture?

Posted December 7, 2020


Answer

Organotypic culture is a technique in which samples of complex tissues or organs are collected from an organism, and artificially perpetuated in a controlled environment in an effort to retain the basic structural organization and functionality of their organ of origin. In recent years, organotypic culture has emerged as a promising technique for the analysis of tissue behavior ex vivo.

Additional resources

Three-dimensional organotypic culture: experimental models of mammalian biology and disease