AAT Bioquest

What is lacZ reporter gene?

Posted December 10, 2019


The E. coli LacZ gene is often used as a reporter gene since it produces a blue product once it is cleaved by the β-galactosidase enzyme. This ‘reports’ whether or not the gene is expressed by the bacteria when grown in a compatible substrate (such as X-gal).

Additional resources

Amplite™ Colorimetric Beta-Galactosidase Assay Kit