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What is the difference between transfection and transformation?
Posted February 25, 2020
Answer
The differences between transfection and transformation are outlined in Table 2.
Table 2.The differences between transfection and transformation.
| Features | Transfection | Transformation |
| Definition | Method of gene transfer in which the genetic material is deliberately introduced | Method of gene transfer in which the genetic material is directly uptaken and incorporated through the cell membrane(s) |
| Target cells | Mammalian cells | Plant, yeast and bacterial cells |
| Acheived by | Chemical, physical and viral methods | Chemical transformation, electroporation and particle bombardment |
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