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What is the molecular weight (mw) of glycogen phosphorylase?
Posted May 30, 2018
molecular weightglycogen phosphorylase
Answer

188 kDa

 

Glycogen phosphorylase is the enzyme responsible for glycogen breakdown in liver and muscle. It exists in two forms, unphosphorylated phosphorylase b and phosphorylase a with two Ser-PO42– groups. Glycogen phosphorylase is a dimer of two identical 94 kDa subunits. It has a total molecular weight of 188 kDa, which is equivalent to 188,000 g/mol.

Additional resources
On the Determination of Molecular Weight of Proteins and Protein Subunits in the Presence of 6 M Guanidine HydrochlorideA Reinvestigation of the Molecular Weight of GlycogenPhosphorylase

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