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What level of protein structure is not disturbed by denaturing?
Posted June 22, 2020
Antibodies and ProteomicsPeptide and OligonucleotideProtein
Answer

The primary structure of a proteins is not disturbed, because the denaturation reactions are not strong enough to break the covalent peptide bonds.

Additional resources
Amplite™ Fluorimetric Fluorescamine Protein Quantitation Kit *Blue Fluorescence*Amplite™ Rapid Colorimetric Total Protein Thiol Quantitation Assay KitBranden, C. I., & Tooze, J. (2012). Introduction to protein structure. Garland Science.Tanford, C. (1968). Protein denaturation. In Advances in protein chemistry (Vol. 23, pp. 121-282). Academic press.

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