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What level of protein structure is not disturbed by denaturing?
Posted June 22, 2020
Antibodies and ProteomicsPeptide and OligonucleotideProtein
Answer
The primary structure of a proteins is not disturbed, because the denaturation reactions are not strong enough to break the covalent peptide bonds.
Additional resources
Amplite® Fluorimetric Fluorescamine Protein Quantitation Kit *Blue Fluorescence*Amplite® Rapid Colorimetric Total Protein Thiol Quantitation Assay KitBranden, C. I., & Tooze, J. (2012). Introduction to protein structure. Garland Science.Tanford, C. (1968). Protein denaturation. In Advances in protein chemistry (Vol. 23, pp. 121-282). Academic press.

What are the different forms of peptide bonds?How do acids and bases denature a protein?What catalyzes the formation of peptide bonds?What are the main interactions that stabilize each level of protein structure?What is the relationship between protein structure and protein function?