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What part of the DNA strand does Hoechst bind to?

Posted May 6, 2021


Nucleus
DNA and RNA
Physiological Probes
Answer

Hoechst binds to the minor groove of double-stranded DNA with a marked preference for AT (adenine-thymine)-rich sequences.

Additional resources

Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopy

Hoechst 33342 *Ultrapure Grade*

oechst 33258 *CAS 23491-45-4*

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Location: Home / Frequently Asked Questions (FAQ) / What part of the DNA strand does Hoechst bind to?
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