logo
Products
Services
Resources
Selection Guides
About
What part of the DNA strand does Hoechst bind to?
Posted May 6, 2021
NucleusDNA and RNAPhysiological Probes
Answer
Hoechst binds to the minor groove of double-stranded DNA with a marked preference for AT (adenine-thymine)-rich sequences.
Additional resources
Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopyHoechst 33342 *Ultrapure Grade*oechst 33258 *CAS 23491-45-4*

How do I increase the intensity of PCR bands?What is the difference between G1 and S phase in the cell cycle?What is the best lysis buffer for protein extraction?What is the best concentration to use with Hoechst?What is stringency in hybridization?