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AAT Bioquest

Why do we use geometric mean concentration for antibody titer?

Posted April 24, 2020


Answer

Geometric mean concentration is used for antibody titers because the titer data usually does not fit a linear scale. When the data is skewed and not normally distributed, it is better to calculate the geometric mean instead of the arithmetic mean, which may not give a good representation of the results.

Additional resources

Johnson, E., & Lowe, J. (2005). When is the right time to vaccinate against Erysipelas rhusiopathiae in growing pigs? Journal of Swine Health and Production, 13(2), 114-115.