AAT Bioquest

How does the cell membrane change over time?

Posted November 21, 2022


The cell membrane is a dynamic, selectively permeable structure made up primarily of lipids, proteins, and cholesterol. Different types of molecules and water may move across the membrane briefly for a number of different reasons. The various processes that take place within and across the cell membrane causes it to gradually lose its integrity over time. 

There are several other changes that may occur. The ratio of lipids and proteins in the cell membrane can change. This is because the lipids and proteins get damaged by certain molecules in the body during the lifetime of the cell. In addition, the number and type of proteins in the cell membrane may change depending on the cell’s requirements.  

The amount of cholesterol may also increase with a decrease in temperature, in order to maintain membrane fluidity. 

Additional resources

Do changes in the cell membrane structure induce the generation of lipid peroxidation products which serve as first signalling molecules in cell to cell communication?

Plasma Membrane

Cell Navigator® Cell Plasma Membrane Staining Kit *Green Fluorescence*