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AAT Bioquest

What are the advantages of adsorption immobilization?

Posted February 22, 2024


Answer

Adsorption is an enzyme immobilization technique in which interactions such as hydrophobic forces and salt bridges are used to attach enzymes onto the surface of a solid support material. 

Advantages of Adsorption:

  • Reagents are not required
  • Minimum activation requirements
  • No pore diffusion limitation
  • Minimal drop in enzyme activity
  • Minimum effect on an enzyme
  • High enzyme loading efficiency
  • The adsorbed enzyme can be regenerated, recycled, and reused
  • Straightforward and cost-effective technique
Additional resources

Improved adsorption reactions, kinetics and stability for model and therapeutic proteins immobilised on affinity resins

Enzymes