AAT Bioquest

What are the advantages of whole genome sequencing?

Posted June 24, 2022


Whole genome sequencing is a laboratory process that involves sequencing the whole genome, including both the coding and noncoding regions. This offers researchers several advantages: 

  • Delivers a comprehensive, base-by-base view of the complete genome
  • Capable of detecting both large and small variants including single nucleotide variants
  • Enables the identification of potential causative variants that facilitates follow-up studies of gene expression and regulation mechanisms 
  • Provides vast volumes of data in a short amount of time 
  • Is ideal for identifying causative variants and novel genome assembly 
Additional resources

From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic