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What are the applications of carbocyanine dyes?
Posted January 16, 2024
DiDDiIDiODiRDiSNeuronal tracingfunctional imaging of neurons
Answer

Carbocyanine dyes are a class of highly fluorescent dyes. They have a wide range of applications including but not limited to: 

  • Labeling plasma membranes
  • Retrograde and anterograde labeling in fixed tissue
  • Labeling and visualizing blood vessels
  • Studying living neurons of identified origin in long-term cultures 
  • Simultaneous visualization of vasculature and surrounding tissue structures
  • Mediating imaging and targeted drug delivery for human brain tumor
Additional resources
Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures Neurodegeneration & Amyloid Staining MM 4-64 [N-(3-Triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide] DiIC18(3)-DS [1,1-Dioctadecyl-3,3,3,3-tetramethylindocarbocyanine-5,5-disulfonic acid]

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