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What are the classifications based on the types of probes used?
Posted September 11, 2024
Answer
Types of microarrays based on the types of probes used include but not limited to:
- DNA microarrays measure DNA or use DNA in their detection system. The four types of DNA microarrays include SNP, cDNA, BAC, and oligo DNA microarrays.
- Tissue microarrays create paraffin blocks from tissue samples, which are then used for pathology studies. They combine tissue cores from multiple donors into a single array.
- Antibody microarrays contain capture antibodies for detecting specific antigens. carbohydrate arrays are used to study carbohydrate binding proteins and analyze protein-glycan interactions.
- MMChipsanalyze data from different laboratories and study interactions between DNA and proteins. Techniques used include ChiP-chip and ChiP-Seq. Peptide microarrays are used to study protein–protein interactions and optimize these interactions.
- Protein microarraysare used to analyze a large number of proteins simultaneously. The three types are analytical protein microarrays, reverse-phase protein microarrays, and functional protein microarrays.
- Cellular microarrays are used to screen large chemical and genomic libraries and also study cellular environments.