Basis of differentiation | Alpha Galactosidase | Beta Galactosidase |
Definition | Is an enzyme that breaks down substrates that contain alpha galactosidase residues such as glycoproteins | Is an enzyme that breaks down beta galactosidase into monosaccharides |
Molecular weight | 101 Kd | 465 kDa |
Substrates | Glycoproteins, glycolipids, polysaccharides, | Lactose, ganglioside GM1, lactosylceramides |
Gene encoded | GLA gene | GLA gene |
Disease associated with defects | Fabry disease | GM1 gangliosidosis, Morquio B disease |