What are the differences between fatty acid synthesis and beat-oxidation?

Question

Accepted Answer

Basis of differentiation

Fatty acid synthesis

Beta oxidation

Definition

Refers to a multi-step metabolic process in which fatty acids are produced from precursor molecule acetyl CoA  and NADPH molecules through a series of anabolic reactions by enzymes

Is a multi-step metabolic process in which fatty acid molecules are broken down to produce energy through a series of catabolic reactions by enzymes

Initiation of the process

Is initiates by acyl group carrier (ACP)

Is initiated by with coenzyme A (CoA)

Occurrence

Occurs in the cytoplasm in both prokaryotes and eukaryotes

Occurs in the cytoplasm of prokaryotes and mitochondria in eukaryotes

Type of reaction

Is an anabolic reaction

Is a catabolic process

Enzymes involved

Is catalyzed by the enzyme fatty acid synthase, a multi-enzyme complex

Is catalyzed by different enzymes at different stages of the oxidation process

Relationship with Energy

Energy is used by this process

Energy is released during this process

Relationship with ATP

Uses ATP

Produces high-energy molecule ATP

Reductants Used

Uses one reductant:

NADPH (Nicotinamide Adenine Dinucleotide Phosphate Hydrogen)

Uses 2 reductants:

NADH (Nicotinamide Adenine Dinucleotide Phosphate Hydrogen)
FADH (reduced form of Flavin Adenine Dinucleotide)

Basis of differentiation	Fatty acid synthesis	Beta oxidation
Definition	Refers to a multi-step metabolic process in which fatty acids are produced from precursor molecule acetyl CoA and NADPH molecules through a series of anabolic reactions by enzymes	Is a multi-step metabolic process in which fatty acid molecules are broken down to produce energy through a series of catabolic reactions by enzymes
Initiation of the process	Is initiates by acyl group carrier (ACP)	Is initiated by with coenzyme A (CoA)
Occurrence	Occurs in the cytoplasm in both prokaryotes and eukaryotes	Occurs in the cytoplasm of prokaryotes and mitochondria in eukaryotes
Type of reaction	Is an anabolic reaction	Is a catabolic process
Enzymes involved	Is catalyzed by the enzyme fatty acid synthase, a multi-enzyme complex	Is catalyzed by different enzymes at different stages of the oxidation process
Relationship with Energy	Energy is used by this process	Energy is released during this process
Relationship with ATP	Uses ATP	Produces high-energy molecule ATP
Reductants Used	Uses one reductant: NADPH (Nicotinamide Adenine Dinucleotide Phosphate Hydrogen)	Uses 2 reductants: NADH (Nicotinamide Adenine Dinucleotide Phosphate Hydrogen) FADH (reduced form of Flavin Adenine Dinucleotide)

Basis of differentiation

Fatty acid synthesis

Beta oxidation

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