Refers to the T cell development process in the thymus by the binding of T-cell receptors (TCRs) of mature T-cells to the self-antigens presented by Major Histocompatibility Complex (MHC) of thymocytes
Is responsible for the maturation of thymocytes
Results in the maturation of thymocytes into either CD8+ (cytotoxic) T-cells or CD4+ (helper) T-cells