Basis of differentiation | Primary active transport | Secondary active transport |
Definition | Primary active transport is the transport of molecules against a concentration gradient through the use of energy generated by ATP | Secondary active transport is the transport of two distinct molecules across a membrane using energy in other forms than ATP |
Number of molecules transported | A single molecule is transported | Two types of molecules are transported simultaneously |
Energy source | Uses energy generated from ATP | The concentration gradient of driving ion supplies energy for the transport of the driving ion/molecule against its concentration gradient |
Number of substances transported | May transport one or more substances | Must transport more than one substance |
Types of transmembrane proteins used | Transmembrane proteins are specific to the ion transported through them | Both antiporters and symporters are used in secondary active transport |
Types of molecules transported | Ions like sodium, potassium, and calcium are transported across cell membrane | Ions like sodium act as the driving molecules |
Examples | Sodium potassium pump, calcium pump in muscles | Glucose-sodium pump, sodium-potassium pump |