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AAT Bioquest

What are the examples of covalent inhibitors?

Posted April 4, 2024


Answer

The most well-known examples of covalent inhibitors include β-lactams, a group of antibacterial agents that includes penicillin and cephalosporin. Other examples include dimethyl fumarate, zanubrutinib, dacomitinib, and ibrutinib.  

Additional resources

Covalent Inhibition in Drug Discovery

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Amplite® Fluorimetric Coenzyme A Quantitation Kit *Green Fluorescence*

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