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AAT Bioquest

What are the properties of chromosomes?

Posted February 3, 2024


Answer

Chromosomes are long thread-like structures made up of protein and a single molecule of DNA (deoxyribonucleic acid). The DNA is wrapped around spool-like proteins called histones. Chromosomes exhibit five crucial properties that are integral to genetic information and cell function: 

  1. Replication: Replication involves the synthesis of a new DNA molecule that is identical to the parent DNA molecule. This property ensures that the genetic information is faithfully transmitted to daughter cells resulting in the generation of an identical copy of the parent DNA molecule.  
  2. Transcription: During transcription, a DNA template is used to synthesize messenger RNA (mRNA) molecules, which carries genetic instructions from the DNA to the cellular components responsible for protein synthesis.  
  3. Changing appearance: Chromosomes undergo noticeable changes in appearance during different stages of the cell cycle, particularly during cell division, ensuring that genetic material is efficiently and equally distributed to daughter cells during cell division. 
  4. Repair: Chromosomes possess a remarkable capacity to repair damaged sections of DNA, which can occur during DNA replication or due to exposure to the environment. This is crucial for maintaining the stability and integrity of the genetic code and preventing mutations. 
  5. Mutation: Chromosomes may undergo beneficial mutations that help the organism better adapt to their changing environment, or they may undergo harmful mutations that may have a deleterious effect on the organism and increase their susceptibility to diseases.  
Additional resources

The material properties of mitotic chromosomes

DNA and RNA Quantitation

Helixyte™ Green Fluorimetric dsDNA Quantitation Kit *Optimized for Broad Dynamic Range*