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AAT Bioquest

What are the pros of MACS?

Posted May 9, 2023


Answer

MACS (Magnetic-activated cell sorting) is a simple cell-sorting method that uses a magnetic field to isolate the desired cell. One of the most notable pros of MACS is that it significantly reduces the amount of time required to complete the cell-sorting process. For example, it is about 4 to 6 times faster than FACS, another widely-used cell-sorting method. Using MACS, researchers can run a higher quantity of samples in a shorter period of time. Another pro of MACS is that it reduces the total quantity of cells that need to be sorted. 

Additional resources

Quantitative Magnetic Separation of Particles and Cells Using Gradient Magnetic Ratcheting

Fluorescence Activated Cell Sorting (FACS)

Flow Cytometry Reagents

ReadiUse™ CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4*