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AAT Bioquest

What are the subclasses of immunoglobulin A (IgA)?

Posted July 31, 2024


Answer

There are two subclasses of Immunoglobulin A (IgA) in humans – IgA1 and IgA2. These subclasses differ in the molecular mass of their heavy chains, structure of their hinge region, and concentration in serum. 

Additional resources

Subclass distribution of IgA antibodies in saliva and serum after immunization with Haemophilus influenzae type b conjugate vaccines

Antibodies and Proteomics

Purified Mouse Anti-human IgA Antibody *AD3, monoclonal*