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What are the types of regulatory T cells?
Posted August 18, 2023
Antibodies and Proteomics BioconjugationAntibody and Protein LabelingCD4+ T CellsCluster of Differentiation (CD Antibodies)
Answer
Regulatory T cells or Tregs are white blood cells that are involved in regulating the body’s immune response and preventing it from over-reacting to harmful invaders known as antigens. There are two types of regulatory T cells – natural Tregs and Induced Tregs. 
Natural Tregs: 
  • Develop in the thymus during T cell maturation 
  • Target self-antigens and help to control autoimmune inflammation
Induced Tregs: 
  • Are derived from naïve CD4+ T cells in the periphery
  • Target foreign antigens and neoantigens 
  • Get activated on receiving signals from small proteins called cytokines
Additional resources
The Development and Function of Regulatory T CellsCD4 (Leu3, T4) iFluor® 488 Anti-human CD4 Antibody *OKT-4*

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