AAT Bioquest

What is AKT?

Posted September 27, 2023


ATK, also called protein kinase B or PKB, is a serine/threonine specific protein kinase which plays a vital role in regulating the balance between cell death and survival pathways. AKT is made up of three homologous isoforms which are: AKT 1, AKT2, and AKT3. AKT has various downstream effects and targets over 100 different substrates. 

Additional resources

The protein kinase B/Akt signalling pathway in human malignancyv

Cell Signaling Pathways

Serine/threonine-protein kinase AKT Inhibitors (IC50, Ki)