AAT Bioquest

What is produced in fatty acid oxidation?

Posted July 1, 2022


Energy is produced in fatty acid oxidation. Fatty acid oxidation is a metabolic process in which fatty acid molecules are broken down to produce energy. The process starts with fatty acids penetrating the cell wall and entering the cytoplasm where they bind to CoA to form fatty acyl CoA. The cytosolic acyl CoA is transported to the mitochondria. Here it undergoes β-oxidation over four stages- dehydrogenation, hydration, oxidation, and thiolysis. Each of these stages is catalyzed by a different enzyme. The end product of the four stages is acetyl-CoA, which enters the Krebs cycle or citric acid cycle. This is a metabolic process that produces ATP, which is used as energy. 

Additional resources

Screen Quest™ Fluorimetric Fatty Acid Uptake Assay Kit

Intermediates and products formed during fatty acid alpha-oxidation in cucumber (Cucumis sativus)