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AAT Bioquest

What is the difference between isomerases and transferases?

Posted January 16, 2024


Answer

Basis of differentiation

Isomerases

Transferases

Definition

Isomerases are a class of enzymes which accelerates chemical reactions where the molecules undergo rearrangements in their structure

Transferases are enzymes which catalyze the transfer of functional groups from one molecule to another

Substrate

Converts a substrate molecule into its isomeric form (same molecular formula but differing structural arrangement)

Uses a donor and acceptor molecules in which the functional group is transferred from the donor to the acceptor

Functional groups

Catalyzes the conversion of functional groups

Transferases function to transfer functional groups like methyl groups between molecules via a nucleophilic substitution reaction

Examples

3,2-enoylCoA isomerase

Acyltransferase

Additional resources

Cis Trans Isomerase

Enzymes

Amplite® Colorimetric Aspartate Aminotransferase (AST) Assay Kit