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AAT Bioquest

What is the significance of cDNA?

Posted March 1, 2023


Answer

cDNA is complementary DNA that is synthesized from mRNA (messenger RNA). It is useful for cloning and expressing specific genes. Scientists can also create cDNA libraries, enabling them to study sequences specific to a given tissue and develop shareable databases. cDNA can be used for RNA quantitation, which allows researchers to do more in-depth clinical research and protect the genetic makeup of an endangered species. 

Additional resources

Evaluation of vector-primed cDNA library production from microgram quantities of total RNA

DNA and RNA Quantitation

ReadiScript™ RT Reverse Transcription Kit