AAT Bioquest

What is the Svedberg coefficient?

Posted December 12, 2022


The Svedberg coefficient is a nonlinear function. The Svedberg coefficient is the measure of the rate of sedimentation of a molecule or particle; it is the ratio of a particle's sedimentation speed to the centrifugal field causing the sedimentation. As an example,  the 70S ribosome  has sedimentation times of 70 X 10^-13, 50 X 10^-13, and 30 X10^-13 seconds. The 70S ribosome is the largest and will sediment the fastest. On the other hand, the 30S is the smallest ribosome and will sediment the slowest. 

Additional resources

The Svedberg Lecture 2017. From nano to micro: the huge dynamic range of the analytical ultracentrifuge for characterising the sizes, shapes and interactions of molecules and assemblies in Biochemistry and Polymer Science

Cell Structures and Organelles

Cell Navigator® Live Cell Endoplasmic Reticulum (ER) Staining Kit *Green Fluorescence*