Sometimes a single inhibitor may not be sufficient since protease inhibitors vary based on the type of proteases they target. So, using a designed cocktail of inhibitors can provide better protection for proteins in experiments. Additionally, using pre-made cocktails can be cost-effective compared to assembling individual inhibitors. By purchasing only the necessary amount of inhibitors in a ready-to-use format, researchers can avoid overspending on excess reagents that may go unused. Premade cocktails are also convenient to use, eliminating the need for extensive knowledge about individual inhibitors and their concentrations. Researchers can simply add the recommended amount of the cocktail to their samples. Lastly, premade protease inhibitor cocktails offer consistent results as they are already tested and optimized for various experimental conditions. They are produced in larger batches, ensuring uniformity across different batches and saving time.