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AAT Bioquest

What type of DNA is found in humans?

Posted June 12, 2023


Answer

The type of DNA found in humans at neutral pH and physiological salt concentrations is B-DNA. 

B-DNA is the classic form of DNA. It features a right-handed double helical structure with the two DNA strands flowing in opposite directions. The strands have an uneven structure with alternating primary grooves and minor grooves. It has a winding width of 2 nm. 

The core of B-DNA is composed of nitrogenous bases and the backbone is composed of sugar phosphates linked together by phosphodiester linkages. 

Additional resources

The regulation of DNA supercoiling across evolution

DNA and RNA Quantitation

Helixyte™ Green Fluorimetric dsDNA Quantitation Kit *Optimized for Broad Dynamic Range*