What would happen if the nucleus had no membrane?

If the nucleus had no membrane, all metabolic functioning of the cell would stop and the cell would die. The nucleus would lose control of the cell and fail to carry out its different functions which can lead to compromised cellular homeostasis and death. These functions include producing new proteins, carrying out cellular reproduction, DNA repair, and regulation of organelles. The nuclear membrane is crucial to the nucleus, as it acts as a physical barrier that separates the nucleus from the cytoplasm. Without the membrane, there would be a loss of compartmentalization within the cell. This in turn would cause the mixing of nuclear components with cytoplasmic components, and consequently alter cellular processes. The cellular membrane also plays an important role in regulating gene expression by controlling the movement of molecules into and out of the nucleus. If there was no membrane, there would be a loss of regulation of these molecules and thus gene expression would be affected.