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Where do CD8+ T cells originate?
Posted August 24, 2023
Antibodies and Proteomics BioconjugationAntibody and Protein LabelingCD4+ T CellsCluster of Differentiation (CD Antibodies)
Answer
CD8+ cells originate in the bone marrow.
CD8+ cells are also called cytotoxic T lymphocytes or CTLs. They originate from lymphoid progenitor cells in the bone marrow. Immature T cells or thymocytes migrate from the bone marrow to the thymus where they undergo several DNA rearrangements resulting in a diversity of TCRs that are capable of recognizing antigens from foreign or intracellular pathogens.