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Which cellular organelles are involved in initiation of the intrinsic pathway of apoptosis?
Posted November 7, 2022
Apoptosis and NecrosisCell Viability AssaysCellular ProcessesCellular Structures and OrganellesMitochondriamitochondria membrane potential
Answer
Mitochondria are the main cellular organelles that are involved in initiation of intrinsic pathway of apoptosis. MOMP (Mitochondria Outer Membrane Permeabilization) initiates the intrinsic apoptosis pathway, triggering the release ofpro-apoptotic proteins from the mitochondrial intermembrane space into the cytoplasm.